Aktivitas Antimikrobia Ekstrak Etanolik Daun Senggugu (Clerodendron serratum [L.] Spreng) terhadap Candida albicans ATCC 10231

• Main Authors: , DYAH MEGANTI K, , Dr. Yekti Asih Purwestri, S.Si., M.Si.
• Format: Theses and Dissertations NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2014
• Subjects: ETD
• Online Access: https://repository.ugm.ac.id/127486/; http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=67741
• Institution: Universitas Gadjah Mada

Candidiasis is a disease caused by Candida albicans. Candidiasis can be prevented by synthetic antibiotics, but it may develop resistancy. The purpose of this research is to study the phytochemicals content and concentration of ethanolic extract of senggugu leave (Clerodendron serratum [L.] Spreng) to inhibit the growth of C. albicans. In this study ethanolic extract of senggugu leave was used for TLC test and antimicrobial activity test against C. albicans. In study the concentration of ethanol extracts applied were 0%, 3%, 6%, 9%, 12%, 15%, 20%, 25%, 50% and 75%. Nystatin 250,000 U/L was used as a positive control. TLC analysis used silica Gel F254 as the stationary phase and chloroform : ethanol 70% (9:2) as the mobile phases. The antimicrobial activity test was done by calculating the inhibitory zone formed using standard diffusion method. The results showed that the ethanolic extract contains of alkaloids, flavonoids, terpenoids saponins and tannins, with Rf 0,164