PENGARUH INFEKSI Mycobacterium tuberculosis TERHADAP SISTEM IMUN DI DALAM PARU-PARU DAN LIMFA
Tuberculosis is one of the diseases which caused the highest mortality in developing countries. This disease is caused by an agent called Mycobacterium tuberculosis. The main targets of the agent are macrophages and important immune system cells. A better understanding of the interaction between Myc...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/131515/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=72011 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | Tuberculosis is one of the diseases which caused the highest mortality in
developing countries. This disease is caused by an agent called Mycobacterium tuberculosis.
The main targets of the agent are macrophages and important immune
system cells. A better understanding of the interaction between Mycobacterium tuberculosis
and immune system will contribute to the design of mathematical model
to control tuberculosis. The model is used to understand the effect of Mycobacterium
tuberculosis infection to the immune system in lung. Furthermore, the model
is expanded by adding up dendritic cell population as the immune system to control
Mycobacterium tuberculosis infection in lung and lymph. Model analysis reveals
existence of two equilibrium states, infection free equilibrium and the endemically
infected equilibrium. The equilibriums represent a state of latent or active infection,
depending on the amount of bacteria. |
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