Pengaruh polimorfisme C677T gena methylentetrahydrofolate reductase (MTHFR) terhadap kejadian relaps pada anak dengan Leukemia limfoblastik akut (LLA)
Methotrexate is a key drug in acute lymphoblastic leukemia (ALL) treatment. It inhibits DNA replication by blocking the conversion of 5,10 methylenetetrahydrofolate to 5-methylenetetrahydrofolate by methylene tetrahydrofolate reductase, a critical enzyme involved in folate metabolism, DNA methylatio...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/133243/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=73807 |
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| Institution: | Universitas Gadjah Mada |