HUBUNGAN KADAR ADIPONEKTIN DENGAN WAIST TO HEIGHT RATIO, WAIST CIRCUMFERENCE PADA SUBYEK SEHAT
Obesity, especially visceral obesity, has been associated with morbidity and mortality through endocrine and mechanical processes. Clinical manifestations are due to the effects of obesity on the cardiovascular,respiratoric, gastrointestinal, musculoskeletal, immune, and skin systems When there is c...
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| Main Authors: | , |
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| Format: | Theses and Dissertations NonPeerReviewed |
| Published: |
[Yogyakarta] : Universitas Gadjah Mada
2014
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| Subjects: | |
| Online Access: | https://repository.ugm.ac.id/133244/ http://etd.ugm.ac.id/index.php?mod=penelitian_detail&sub=PenelitianDetail&act=view&typ=html&buku_id=73808 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | Obesity, especially visceral obesity, has been associated with morbidity
and mortality through endocrine and mechanical processes. Clinical
manifestations are due to the effects of obesity on the cardiovascular,respiratoric,
gastrointestinal, musculoskeletal, immune, and skin systems When there is
chronic excessive calorie intake, the body will develop metabolic,cellular,and
mechanical adaptations. Central obesity-related disorders has been associated with
abnormal metabolic characteristics of insulin resistance. The presence of excess
fat in the abdomen out of proportion to total body fat is an independent predictor
of morbidityand mortality. BMI and waist circumference is positively correlated
with total body adipose tissue, but waist circumference is a better predictor of
visceral fat than BMI. Waist circumference is used to determine body fat
distribution. An anthropometric measurements which compare between
abdominal circumference with body height , known as the waist to height ratio
(WHtR ) is known to have a better association with metabolic risk factors.
Previous studies demonstrated the role of adiponectin in the pathophysiology of
diseases caused by obesity. The association between waist to height ratio with
adiponectin still remains unknown .
This study aimed to investigate the correlation between WHtRas well as
other obesity measurements with adiponectin. A cross sectional study will be
conducted on male and female subjects with � 35 years of age. Each recruited
subject will undergo a physical examination to assess WHtR, waist circumference
and BMI. Serum samples were collected from subjects to obtain the adiponectin,
blood glucose levels and lipid profiles. Spearman correlation analysis will be
conducted to determine the correlation between adiponectin with each measure of
obesity .Theresultswould be considered as significant if p< 0.05 with 95 % CI . |
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