Uji aktivitas antioksidan jus buah mengkudu (Morinda citrifolia) dan perannya sebagai inhbitor advanced glycation end products (AGEs) akibat reaksi glikosilasi
Background: Mengkudu is a traditional plant with active compound that has antioxidant activity. Diabetes mellitus complication has causative link with AGEs formation that involves free radical. Objective: To know antioxidant activity of mengkudu and the role to inhibit AGEs formation. Methods: This...
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| Format: | Article NonPeerReviewed |
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[Yogyakarta] : Universitas Gadjah Mada
2005
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| Online Access: | https://repository.ugm.ac.id/18500/ http://i-lib.ugm.ac.id/jurnal/download.php?dataId=1291 |
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| Institution: | Universitas Gadjah Mada |
| Summary: | Background: Mengkudu is a traditional plant with active compound that has antioxidant activity. Diabetes mellitus complication has causative link with AGEs formation that involves free radical. Objective: To know antioxidant activity of mengkudu and the role to inhibit AGEs formation.
Methods: This experiment used pre and post test control group design. Antioxidant activity was determined by reacting the mengkudu juice with 2,4 dinitrophenylhydrazin (DNPH) and analyzed with spectrophotometer X=390 nm. AGEs absorbancy was measured every 48 hours until 20 days with spectrophotometer ?=340 nm. Dicarbonyl level was determined with DNPH method that was developed by Uchida and modified by Sadikin.
Result: Antioxidant activity of 0.25 g/mI mengkudu juice (Morinda citrifolia) was 125.46±27.79%. Beside that, mengkudu juice can inhibit advanced glycation end products (AGEs) formation. Conclusion: formationMengkudu juice can decrease AGEs formation and has antioxidant activity.
Key words: antioxidant - mengkudu juice - AGEs - glycosilation |
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