Sifat Hipoglisemik dan Hipolipidemik Kacang Kapri (Pisum sativum LINN) dan Kedelai (Glicine max MERR) Pada Tikus Sprague Dawley Diabetik Induksi Alloksan

• Main Author: Perpustakaan UGM, i-lib
• Format: Article NonPeerReviewed
• Published: [Yogyakarta] : Universitas Gadjah Mada 2002
• Subjects: Jurnal i-lib UGM
• Online Access: https://repository.ugm.ac.id/22977/; http://i-lib.ugm.ac.id/jurnal/download.php?dataId=5904
• Institution: Universitas Gadjah Mada

Hypoglycemic and hypolipidemic properties of Edible podded peas (Pistil?! sativum LINN) and Soy bean (Glvcine max MERR) were evaluated in alloxan-induced diabetic rats. The objectives of this research were to investigate the effects of these legumes on serum glucose, total cholesterol and triacyl glycerol in alloxan-induced diabetic rats. Thirty male Sprague-Dawley (SD) cars (250.300 g) were provided and divided into three groups of ten rats. They were diabetic induced by twice intramuscular injection of alloxan (80 mg/Kg of body weight), then fed with three different diets i.e. Standard (ST), (2) Edible Podded peas (EP) and Soybean (SB) for 28 days. The legumes provided 20% calorie of the total diet calorie. Concentration of serum glucose, total cholesterol and triacyl glycerol were measured before injection and diet intervention (0 day and day 17th) and were monitored in the middle and at the end of diet intervention (day 31'r' and 45th). It was found that alloxan injection increased serum glucose concentration from 63.5 mg/dL to 218.4 mg/dL, total cholesterol and Waryl glycerol concentration increased from 90.7 ing/dL to 136.6 mg/dL and from 108 ing/dL to 147.5 mg1dL, respectively. In 28 days of diet intervention, EP and SB diets decreased the serum glucose concentration by 145.5 ing/dL (67%) and 142.1 mg/dL (65%), respectively, compared to 125.3 mg/dL (57%) in the ST diet. Total cholesterol decreased by 31% and 27% for EP and SB groups. respectively but only 17% for ST rats. intervention of the diets also decreased concentration of triacyl glycerol by 9% and 5%. far EP and SB diets, respectively, but increased by 6% for standard (ST) diet. Kerwords diabetic, alloxan-induced, hypoglycemic, hypolipidemic, Edible podded peas