Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria

Primaquine and tafenoquine are the only licensed drugs with activity against Plasmodium vivax hypnozoites but cause haemolysis in patients with glucose–6–phosphate dehydrogenase (G6PD) deficiency. Malaria also causes haemolysis, leading to the replacement of older erythrocytes with low G6PD activi...

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Main Authors: Ley, Benedikt, Alam, Mohammad Shafiul, Satyagraha, Ari Winasti, Phru, Ching Swe, Thriemer, Kamala, Tadesse, Dagimawie, Shibiru, Tamiru, Hailu, Asrat, Kibria, Mohammad Golam, Hossain, Mohammad Sharif, Rahmat, Hisni, Poespoprodjo, Jeanne R., Khan, Wasif Ali, Simpson, Julie A., Price, Ric N.
Format: Article PeerReviewed
Language:English
Published: PLOS
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Online Access:https://repository.ugm.ac.id/282460/1/202.pdf
https://repository.ugm.ac.id/282460/
https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0010406
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Institution: Universitas Gadjah Mada
Language: English