Anti N-Methyl-D-Aspartate Receptor encephalitis with ovarian teratoma: a dilemma in diagnosis
We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopat...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Medicine, UKM Medical Centre
2016
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| Online Access: | http://journalarticle.ukm.my/9841/1/15._Lee_et_al..pdf http://journalarticle.ukm.my/9841/ http://jsurgacad.com/toc/6/1 |
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| Institution: | Universiti Kebangsaan Malaysia |
| Language: | English |
| Summary: | We report a rare case of altered mental status in a young patient with immature ovarian teratoma. A 22-year-old woman presented with seizures, hallucination, amnesia and orofacial dyskinesia. Examination and investigation revealed an ovarian massand asalphing-oophorectomy was performed. The histopathological examination result showed an immature teratoma grade 2 with thepresence of immature primitive glial tissue. Her CSF N-Methyl-D-Aspartic acid receptor (Anti-NMDAR) antibodytest was positive. N-Methyl-D-Aspartic acid receptor antibody associated limbic encephalitis is an autoimmune antibody-mediated neuropsychiatric disorder. Resection of the tumour and immunotherapy resulted in full recovery. |
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