EXTRATION OF PHENOLIC COMPOUND FROM NEPHELIUM LAPPACEUM LEAVES FOR THE TREATMENT OF DIABETES

There has been an enormous attention in development of unconventional medicines for the treatment of Type 2 diabetes, precisely selection for phytochemicals with the capability to postponement or inhibit glucose absorption. Phenolic compound from Nephelium lappaceum leaves was investigated using...

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Bibliographic Details
Main Author: KHAN, SAIMA
Format: Thesis
Language:English
Published: 2014
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Online Access:http://utpedia.utp.edu.my/21165/1/2014-CHEMICAL-EXTRATION%20OF%20PHENOLIC%20COMPOUND%20FROM%20NEPHELIUM%20LAPPCEUM%20LEAVES%20FOR%20THE%20TREATMENT%20OF%20DIABETES-SAIMA%20KHAN.pdf
http://utpedia.utp.edu.my/21165/
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Institution: Universiti Teknologi Petronas
Language: English
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Summary:There has been an enormous attention in development of unconventional medicines for the treatment of Type 2 diabetes, precisely selection for phytochemicals with the capability to postponement or inhibit glucose absorption. Phenolic compound from Nephelium lappaceum leaves was investigated using Gallic acid as a precursor. The phenolic compound was extracted in 50, 70, 90 and 100% ethanol, methanol, isopropanol and acetone with solid to solvent ratio (10:1 w/v ratio) at 45°C, 60°C and 75°C. The aim of present study was to provide in-vitro confirmation for potential inhibition by FRAP assay, ABTS assay, a-amylase assay and a-glucosidase assay. Characterization of Nephelium Lappaceum Green and Brown leaves was taken in account. The percentage of moisture content was 33.14%o in semi-dried Brown leaves and 51.24% in fresh Green leaves.