Acute oral toxicity evaluation of synbiotic mixture containing Streptococcus salivarius K12 and Musa acuminata aqueous peel extract in Sprague-Dawley rats

• Main Authors: Mohd Fuad, Aalina Sakiina, Arzmi, Mohd Hafiz, Bakar, Muhammad Ekmal, Taib, Izatus Shima, Khuda, Fazle, Nasruddin, Nurrul Shaqinah
• Format: Article
• Language: English; English; English
• Published: Elsevier B.V. on behalf of Institute of Transdisciplinary Health Sciences and Technology and World Ayurveda Foundation 2024
• Subjects: QR Microbiology; RK Dentistry
• Online Access: http://irep.iium.edu.my/117769/7/117769_Acute%20oral%20toxicity%20evaluation%20of%20synbiotic.pdf; http://irep.iium.edu.my/117769/13/117769_Acute%20oral%20toxicity%20evaluation%20of%20synbiotic_Scopus.pdf; http://irep.iium.edu.my/117769/14/117769_Acute%20oral%20toxicity%20evaluation%20of%20synbiotic_WoS.pdf; http://irep.iium.edu.my/117769/; https://doi.org/10.1016/j.jaim.2024.101037
• Institution: Universiti Islam Antarabangsa Malaysia

Background: The combination of S. salivarius K12 and M. acuminata are being used as synbiotic, but its safety evaulation is required. Objective: This study aimed to determine the LD50 of synbiotic containing probiotic Streptococcus salivarius K12 and prebiotic Musa acuminata peel extract. Materials...