A review on the formulation and analysis of anti-diabetic agent: Gliclazide
Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM) and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported to ha...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Trans Tech Publications, Switzerland
2013
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/32319/1/Glaclizide-paper.pdf http://irep.iium.edu.my/32319/ http://www.scientific.net/AMR.810.159 |
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| Institution: | Universiti Islam Antarabangsa Malaysia |
| Language: | English |
| Summary: | Gliclazide is a second generation sulfonylurea, which is used as antidiabetics drug. It is
orally administrated and used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM)
and has duration of action of 12 h or more. Beside its hypoglycaemic effects, gliclazide was reported
to have many other important effects, such as: suppression of platelet functions, antithrombotic
actions, decreased the production of tumour necrosis factor (TNF) á by endothelial cells and other
effects. The unique activities of gliclazide has open a new avenue for the drug development research.
This work is aimed to provide comprehensive information about gliclazide and its current research
activities. |
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