Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
Six new 2-halobenzoylthiourea compounds bearing α- and β-alanine have been successfully synthesized and characterized using CHNS microelemental analysis and spectroscopic methods including FTIR, UV-Vis and NMR. Microelemental analysis data of the compounds were in agreement with the theoretical valu...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Chiang Mai University
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/46121/4/16-03-22-d490d.pdf http://irep.iium.edu.my/46121/7/46121_Synthesis%2C%20Characterization%20and%20Antioxidant%20Activity%20of%202-Halobenzoyl_Scopus.pdf http://irep.iium.edu.my/46121/13/46121_Synthesis%2C%20characterization%20and%20antioxidant%20activity_wos.pdf http://irep.iium.edu.my/46121/ http://it.science.cmu.ac.th/ejournal/journalDetail.php?journal_id=6816 |
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| Institution: | Universiti Islam Antarabangsa Malaysia |
| Language: | English English English |
| Summary: | Six new 2-halobenzoylthiourea compounds bearing α- and β-alanine have been successfully synthesized and characterized using CHNS microelemental analysis and spectroscopic methods including FTIR, UV-Vis and NMR. Microelemental analysis data of the compounds were in agreement with the theoretical values. The FTIR spectra showed the presence of important bands of the compounds while the 1 H-NMR and 13C-NMR exhibited the expected chemical shifts. The compounds exerted weak antioxidant activity in DPPH scavenging test and moderate to good activity in β-carotene bleaching test. The inclusion of halogen atoms has facilitated the released of hydrogen atoms and introduction of α- and β-alanine have increased the β-carotene bleaching and DPPH scavenging activities of the compounds. |
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