Intra-articular injection of chondrogenic induced bone marrow stem cells in a sheep model
In recent year, the use of bone marrow mesenchymal stem cells (BMSCs) implantation has provided an alternative treatment for osteoarthritis ( OA). The objective of this study is to determine whether or not an intra-articular injection of a single dose of autologus chondrogenic induced BMSCs could r...
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| Main Authors: | , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2012
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/46455/1/upm_conference_2012.jpg http://irep.iium.edu.my/46455/ http://vet.upm.edu.my/vam2012.html |
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| Institution: | Universiti Islam Antarabangsa Malaysia |
| Language: | English |
| Summary: | In recent year, the use of bone marrow mesenchymal stem cells (BMSCs) implantation has provided an alternative treatment for osteoarthritis ( OA). The objective of this study is to determine whether or not an intra-articular injection of a single dose of autologus chondrogenic induced BMSCs could retard the progressive destruction of cartilage in a surgically induced osteoarthritis in a sheep. from our findings it is suggested that an intra-articular injection into OA knee joints of sheep with autologus bone marrow stem cells cultured in chondrogenic medium has possibility of retarding the progression of OA. |
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