Antinociceptive activity of asiaticoside in mouse models of induced nociception

• Main Authors: Ayumi, Rasyidah Ryta, Shaik Mossadeq, Wan Mastura, Zakaria, Zainul Amiruddin, Bakhtiar, M. Taher, Kamarudin, Nadhirah, Hisamuddin, Nadia, Talib, Madihah, Sabar, Aina Mardhiah
• Format: Article
• Language: English; English; English
• Published: Georg Thieme Verlag KG Stuttgart 2020
• Subjects: RS Pharmacy and materia medica; RS192 Materia Medica-Pharmaceutical Technology
• Online Access: http://irep.iium.edu.my/80138/1/Planta%20Medica.pdf; http://irep.iium.edu.my/80138/7/80138_Antinociceptive%20Activity%20of%20Asiaticoside%20in%20Mouse_SCOPUS.pdf; http://irep.iium.edu.my/80138/13/80138_Erratum%20Antinociceptive%20Activity%20of%20Asiaticoside%20in%20Mouse_SCOPUS.pdf; http://irep.iium.edu.my/80138/; https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1144-3663
• Institution: Universiti Islam Antarabangsa Malaysia

The antinociceptive property of Centella asiatica extracts is known but the analgesic activity of its bioactive constituent asiaticoside has not been reported. We evaluated the antino- ciceptive activity of orally (p.o.) administered asiaticoside (1, 3, 5, and 10mg/kg) in mice using the 0.6% acetic...