Role of sirtuin 1 (SIRT1) in regulation of autophagy and nuclear factor-kappa Beta (NF-ĸβ) pathways in sorafenib-resistant hepatocellular carcinoma (HCC)

Hepatocellular carcinoma (HCC) remains a major global health problem with high incidence and mortality. Diagnosis of HCC at late stages and tumour heterogeneity in patients with different genetic profiles are known factors that complicate the disease treatment. HCC therapy becomes even more challeng...

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Main Authors: Chan, Hui-Yin *, Thamil Selvee, Ramasamy, Chung, Felicia Fei Lei *, Teow, Sin Yeang *
Format: Article
Published: Springer 2024
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Online Access:http://eprints.sunway.edu.my/2592/
https://doi.org/10.1007/s12013-024-01247-3
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Institution: Sunway University