Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff

Spectaflavoside A, a new potent iron chelating dimeric flavonol glycoside from the rhizomes of Zingiber spectabile Griff

The rhizomes of Zingiber spectabile yielded a new dimeric flavonol glycoside for which the name kaempferol-3-O-(4″-O-acetyl)-α-l-rhamnopyranoside-(I-6,II-8)-kaempferol-3-O-(4″-O-acetyl)-α-l-rhamnopyranoside; spectaflavoside A (1) was proposed, along with kaempferol and its four acetylrhamnosides (2–...

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Bibliographic Details
Main Author: Leong, K.H.
Format: Article
Language:English
Published: Elsevier 2012
Subjects:
Q Science (General)
QD Chemistry
QH301 Biology
QK Botany
R Medicine
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
RV Botanic, Thomsonian, and eclectic medicine
Online Access:http://eprints.um.edu.my/10000/1/1Spectaflavoside_A%2C_a_new_potent_iron_chelating_dimeric_flavonol_glycoside_from_the_rhizomes_of_Zingiber_spectabile_Griff..pdf
http://eprints.um.edu.my/10000/
http://www.sciencedirect.com/science/article/pii/S0960894X12002569
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Institution: Universiti Malaya
Language: English
Description
Summary:The rhizomes of Zingiber spectabile yielded a new dimeric flavonol glycoside for which the name kaempferol-3-O-(4″-O-acetyl)-α-l-rhamnopyranoside-(I-6,II-8)-kaempferol-3-O-(4″-O-acetyl)-α-l-rhamnopyranoside; spectaflavoside A (1) was proposed, along with kaempferol and its four acetylrhamnosides (2–6), demethoxycurcumin (7) and curcumin (8). The structure of spectaflavoside A was elucidated by spectroscopic methods including, 1D and 2D NMR techniques. This is the first report on the occurrence of a dimeric flavonol glycoside in the Zingiberaceae and the second in nature. Spectaflavoside A was found to be a potent iron chelating agent.

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