Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine
Methodology for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β–carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine.
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Wiley-VCH Verlag
2012
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my.um.eprints.103892014-10-15T01:56:08Z http://eprints.um.edu.my/10389/ Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine Kam, T.S. Ziegler, R.E. Tan, S.J. Porco Jr., J.A. QD Chemistry Methodology for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β–carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine. Wiley-VCH Verlag 2012 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10389/1/Development_of_an_Alkaloid.pdf Kam, T.S. and Ziegler, R.E. and Tan, S.J. and Porco Jr., J.A. (2012) Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine. Angewandte Chemie International Edition, 51. pp. 9348-9351. ISSN 1433-7851 DOI: 10.1002/anie.201204093 |
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English |
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QD Chemistry |
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QD Chemistry Kam, T.S. Ziegler, R.E. Tan, S.J. Porco Jr., J.A. Development of an alkaloid–pyrone annulation: synthesis of pleiomaltinine |
| description |
Methodology for the synthesis of alkaloid-pyrones using a novel pyrone annulation of β–carbolines and indoles with 3-siloxy-4-pyrones is reported. The approach has enabled semisynthesis of the unprecedented alkaloid-pyrone pleiomaltinine from the plant-derived indole-alkaloid pleiocarpamine. |
| format |
Article |
| author |
Kam, T.S. Ziegler, R.E. Tan, S.J. Porco Jr., J.A. |
| author_facet |
Kam, T.S. Ziegler, R.E. Tan, S.J. Porco Jr., J.A. |
| author_sort |
Kam, T.S. |
| title |
Development of an alkaloid–pyrone annulation: synthesis of
pleiomaltinine |
| title_short |
Development of an alkaloid–pyrone annulation: synthesis of
pleiomaltinine |
| title_full |
Development of an alkaloid–pyrone annulation: synthesis of
pleiomaltinine |
| title_fullStr |
Development of an alkaloid–pyrone annulation: synthesis of
pleiomaltinine |
| title_full_unstemmed |
Development of an alkaloid–pyrone annulation: synthesis of
pleiomaltinine |
| title_sort |
development of an alkaloid–pyrone annulation: synthesis of
pleiomaltinine |
| publisher |
Wiley-VCH Verlag |
| publishDate |
2012 |
| url |
http://eprints.um.edu.my/10389/1/Development_of_an_Alkaloid.pdf http://eprints.um.edu.my/10389/ |
| _version_ |
1643688787056787456 |