Neuronal transcriptomic responses to Japanese encephalitis virus infection with a special focus on chemokine CXCL11 and pattern recognition receptors RIG-1 and MDA5

• Main Authors: Yu, Shu Pin, Ong, Kien Chai, Perera, David, Wong, Kum Thong
• Format: Article
• Published: Elsevier 2019
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/19968/; https://doi.org/10.1016/j.virol.2018.10.015
• Institution: Universiti Malaya

Japanese encephalitis virus (JEV) causes central nervous system neuronal injury and inflammation. A clear understanding of neuronal responses to JEV infection remains elusive. Using the Affymetrix array to investigate the transcriptome of infected SK-N-MC cells, 1316 and 2737 dysregulated genes (≥ 2...