Fucosterol inhibits the cholinesterase activities and reduces the release of pro-inflammatory mediators in lipopolysaccharide and amyloid-induced microglial cells

Fucosterol inhibits the cholinesterase activities and reduces the release of pro-inflammatory mediators in lipopolysaccharide and amyloid-induced microglial cells

According to the cholinergic hypothesis, memory impairment in patients with Alzheimer’s disease (AD) is associated with the deficit of cholinergic function in the brain. In addition, microglial activation plays an important role in AD by producing pro-inflammatory cytokines, nitric oxide (NO), and p...

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Bibliographic Details
Main Authors: Wong, Chun Hoong, Gan, Sook Yee, Tan, Swee Ching, Gany, Siti Aisya, Ying, Tiong, Gray, Alexander Irvine, Igoli, John, Chan, Elaine Wan Ling, Phang, Siew Moi
Format: Article
Published: Springer Verlag 2018
Subjects:
Q Science (General)
QH Natural history
Online Access:http://eprints.um.edu.my/20373/
https://doi.org/10.1007/s10811-018-1495-1
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Institution: Universiti Malaya

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http://eprints.um.edu.my/20373/
https://doi.org/10.1007/s10811-018-1495-1

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