Is the risk of tenofovir-induced nephrotoxicity similar in treatment-naïve compared to treatment-experienced patients?

• Main Authors: Low, Joo Zheng, Khoo, Su Pei, Nor Azmi, Nuruljannah, Chong, Meng Li, Sulaiman, Helmi, Azwa, Iskandar, Tan, Ching Hooi, Kamarulzaman, Adeeba, Rajasuriar, Reena
• Format: Article
• Published: Wiley 2018
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/21392/; https://doi.org/10.1002/jppr.1392
• Institution: Universiti Malaya

Background: Tenofovir disoproxil fumarate (TDF) is the recommended first-line nucleoside reverse transcriptase inhibitor (NRTI) in the management of human immunodeficiency virus (HIV); however, its use is associated with nephrotoxicity. Aim: To assess if the risks of renal impairment were similar in...