Saccharin: an efficient organocatalyst for the one-pot synthesis of 4-amidocinnolines under metal and halogen-free conditions
A mild and efficient protocol for the one-pot synthesis of 4-amidocinnolines was developed using saccharin as a cheap and eco-friendly organocatalyst and t-butyl nitrite as a metal-free diazotization reagent. The current method has advantages such as cost effectiveness, use of the biodegradable reag...
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| Main Authors: | , , , |
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| Format: | Article |
| Published: |
Springer Verlag
2018
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/21639/ https://doi.org/10.1007/s00706-018-2174-2 |
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| Institution: | Universiti Malaya |