Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches

The structure elucidation of three new alkaloids named isoformosaninol (1), formosaninol (2), and longiflorine (3), isolated from the leaves of Uncaria longiflora var. pteropoda (Miq.) Ridsdale, along with their biosynthetic pathways are discussed. Their absolute structures were determined through a...

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Main Authors: Salim, Fatimah, Yunus, Yusri Mohd, Anouar, El Hassane, Awang, Khalijah, Langat, Moses, Cordell, Geoffrey A., Ahmad, Rohaya
Format: Article
Published: American Chemical Society 2019
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Online Access:http://eprints.um.edu.my/23560/
https://doi.org/10.1021/acs.jnatprod.8b00380
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Institution: Universiti Malaya
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spelling my.um.eprints.235602020-01-24T01:08:46Z http://eprints.um.edu.my/23560/ Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches Salim, Fatimah Yunus, Yusri Mohd Anouar, El Hassane Awang, Khalijah Langat, Moses Cordell, Geoffrey A. Ahmad, Rohaya Q Science (General) QD Chemistry The structure elucidation of three new alkaloids named isoformosaninol (1), formosaninol (2), and longiflorine (3), isolated from the leaves of Uncaria longiflora var. pteropoda (Miq.) Ridsdale, along with their biosynthetic pathways are discussed. Their absolute structures were determined through a combination of physical data interpretation and quantum chemical calculations using the time-dependent density functional theory (TDDFT) method. Copyright © 2019 American Chemical Society and American Society of Pharmacognosy. American Chemical Society 2019 Article PeerReviewed Salim, Fatimah and Yunus, Yusri Mohd and Anouar, El Hassane and Awang, Khalijah and Langat, Moses and Cordell, Geoffrey A. and Ahmad, Rohaya (2019) Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches. Journal of Natural Products, 82 (11). pp. 2933-2940. ISSN 0163-3864 https://doi.org/10.1021/acs.jnatprod.8b00380 doi:10.1021/acs.jnatprod.8b00380
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic Q Science (General)
QD Chemistry
spellingShingle Q Science (General)
QD Chemistry
Salim, Fatimah
Yunus, Yusri Mohd
Anouar, El Hassane
Awang, Khalijah
Langat, Moses
Cordell, Geoffrey A.
Ahmad, Rohaya
Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
description The structure elucidation of three new alkaloids named isoformosaninol (1), formosaninol (2), and longiflorine (3), isolated from the leaves of Uncaria longiflora var. pteropoda (Miq.) Ridsdale, along with their biosynthetic pathways are discussed. Their absolute structures were determined through a combination of physical data interpretation and quantum chemical calculations using the time-dependent density functional theory (TDDFT) method. Copyright © 2019 American Chemical Society and American Society of Pharmacognosy.
format Article
author Salim, Fatimah
Yunus, Yusri Mohd
Anouar, El Hassane
Awang, Khalijah
Langat, Moses
Cordell, Geoffrey A.
Ahmad, Rohaya
author_facet Salim, Fatimah
Yunus, Yusri Mohd
Anouar, El Hassane
Awang, Khalijah
Langat, Moses
Cordell, Geoffrey A.
Ahmad, Rohaya
author_sort Salim, Fatimah
title Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
title_short Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
title_full Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
title_fullStr Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
title_full_unstemmed Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches
title_sort absolute configuration of alkaloids from uncaria longiflora through experimental and computational approaches
publisher American Chemical Society
publishDate 2019
url http://eprints.um.edu.my/23560/
https://doi.org/10.1021/acs.jnatprod.8b00380
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