Absolute Configuration of Alkaloids from Uncaria longiflora through Experimental and Computational Approaches

• Main Authors: Salim, Fatimah, Yunus, Yusri Mohd, Anouar, El Hassane, Awang, Khalijah, Langat, Moses, Cordell, Geoffrey A., Ahmad, Rohaya
• Format: Article
• Published: American Chemical Society 2019
• Subjects: Q Science (General); QD Chemistry
• Online Access: http://eprints.um.edu.my/23560/; https://doi.org/10.1021/acs.jnatprod.8b00380
• Institution: Universiti Malaya

The structure elucidation of three new alkaloids named isoformosaninol (1), formosaninol (2), and longiflorine (3), isolated from the leaves of Uncaria longiflora var. pteropoda (Miq.) Ridsdale, along with their biosynthetic pathways are discussed. Their absolute structures were determined through a...