Genome sequencing and phylogenetic reconstruction reveal a potential fourth rhinovirus species and its worldwide distribution
Genome sequences of members of a potential fourth rhinovirus (RV) species, provisionally denoted as rhinovirus A clade D, from patients with acute respiratory infection were determined. Bayesian coalescent analysis estimated that clade D emerged around the 1940s and diverged further around 2006-2007...
محفوظ في:
المؤلفون الرئيسيون: | , , , |
---|---|
التنسيق: | مقال |
منشور في: |
Springer Verlag (Germany)
2021
|
الموضوعات: | |
الوصول للمادة أونلاين: | http://eprints.um.edu.my/26501/ |
الوسوم: |
إضافة وسم
لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!
|
الملخص: | Genome sequences of members of a potential fourth rhinovirus (RV) species, provisionally denoted as rhinovirus A clade D, from patients with acute respiratory infection were determined. Bayesian coalescent analysis estimated that clade D emerged around the 1940s and diverged further around 2006-2007 into two distinctive sublineages (RV-A8-like and RV-A45-like) that harbored unique ``clade-defining'' substitutions. Similarity plots and bootscan mapping revealed a recombination breakpoint located in the 5MODIFIER LETTER PRIME-UTR region of members of the RV-A8-like sublineage. Phylogenetic reconstruction revealed the distribution of clade D viruses in the Asia Pacific region and in Europe, underlining its worldwide distribution. |
---|