Discovery of small molecule inhibitors against the NS3/4A serine protease of Hepatitis C virus genotype 3 via high-throughput virtual screening and in vitro evaluations
The hepatitis C virus (HCV) consists of eight genotypes and 90 subtypes, with genotype (GT) 3 being the second most common globally and is linked to higher incidences of steatosis and rapid development of fibrosis and cirrhosis. The NS3/4A serine protease, a heterodimer complex of two HCV non-struct...
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| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Malaysian Society for Parasitology
2020
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/36458/ |
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| Institution: | Universiti Malaya |