Water-soluble compounds from Lignosus rhinocerus TM02 ® (xLr™) modulate ACE2 activity and inhibit its interaction with SARS-CoV-2 spike-protein

Water-soluble compounds from Lignosus rhinocerus TM02 ® (xLr™) modulate ACE2 activity and inhibit its interaction with SARS-CoV-2 spike-protein

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a coronavirus that causes COVID-19 by attaching its spike protein (S-protein) to the ACE2 receptor on host cells. This interaction is critical for viral entry and infection. Water-soluble compounds found in the medicinal mushroom Lignos...

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Bibliographic Details
Main Authors: Goh, Neng-Yao, Yap, Yeannie Hui-Yeng, Ng, Chyan Leong, Kong, Boon Hong, Ng, Szu-Ting, Tan, Chon-Seng, Razif, Muhammad Fazril Mohamad, Fung, Shin Yee
Format: Article
Published: Elsevier 2024
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/45173/
https://doi.org/10.1016/j.fbio.2024.104232
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Institution: Universiti Malaya

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http://eprints.um.edu.my/45173/
https://doi.org/10.1016/j.fbio.2024.104232

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