Biocatalytic Generation of o-Quinone Imines in the Synthesis of 1,4-Benzoxazines and Its Comparative Green Chemistry Metrics

Biocatalytic Generation of o-Quinone Imines in the Synthesis of 1,4-Benzoxazines and Its Comparative Green Chemistry Metrics

1,4-Benzoxazines are important motifs in many pharmaceuticals and can be formed by a reaction sequence involving the oxidation of o-aminophenols to their corresponding quinone imine followed by an in situ inverse electron demand Diels-Alder (IEDDA) cycloaddition with a suitable dienophile. Reported...

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Bibliographic Details
Main Authors: Tehami, Maryam, Imam, Hasan Tanvir, Abdullah, Iskandar, Hosford, Joseph, Wong, Xiao Juie, Rahman, Noorsaadah Abd, Wong, Lu Shin
Format: Article
Published: American Chemical Society 2024
Subjects:
Q Science (General)
QD Chemistry
Online Access:http://eprints.um.edu.my/45667/
https://doi.org/10.1021/acssuschemeng.3c06758
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Institution: Universiti Malaya

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http://eprints.um.edu.my/45667/
https://doi.org/10.1021/acssuschemeng.3c06758

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