Berberine and RNAi-Targeting Telomerase Reverse Transcriptase (TERT) and/or Telomerase RNA Component (TERC) Caused Oxidation in Colorectal Cancer Cell Line, HCT 116: An Integrative Approach using Molecular and Metabolomic Studies

Colorectal cancer (CRC) is the most common cancer in both men and women and is associated with increased telomerase levels and activity. The potential downstream effects of TERT and/or TERC downregulation by berberine (a telomerase inhibitor) or RNA interference (RNAi) on various target RNAs, protei...

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Bibliographic Details
Main Authors: Samad, Muhammad Azizan, Saiman, Mohd Zuwairi, Majid, Nazia Abdul, Karsani, Saiful Anuar, Yaacob, Jamilah Syafawati
Format: Article
Published: Humana Press 2024
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Online Access:http://eprints.um.edu.my/45802/
https://doi.org/10.1007/s12013-023-01210-8
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Institution: Universiti Malaya