Berberine and RNAi-Targeting Telomerase Reverse Transcriptase (TERT) and/or Telomerase RNA Component (TERC) Caused Oxidation in Colorectal Cancer Cell Line, HCT 116: An Integrative Approach using Molecular and Metabolomic Studies
Colorectal cancer (CRC) is the most common cancer in both men and women and is associated with increased telomerase levels and activity. The potential downstream effects of TERT and/or TERC downregulation by berberine (a telomerase inhibitor) or RNA interference (RNAi) on various target RNAs, protei...
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| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Humana Press
2024
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/45802/ https://doi.org/10.1007/s12013-023-01210-8 |
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| Institution: | Universiti Malaya |