Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis

Platanosides from Platanus x acerifolia: New molecules, SAR, and target validation of a strong lead for drug-resistant bacterial infections and the associated sepsis

Three undescribed (1-3) and nine known (4-12) platanosides were isolated and characterized from a bioactive extract of the May leaves of Platanus x acerifolia that initially showed inhibition against Staphylococcus aureus. Targeted compound mining was guided by an LC-MS/MS-based molecular ion networ...

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Main Authors: Wu, Xi-Ying, Zhao, Ze-Yu, Osman, Ezzat E. A., Wang, Xiao-Juan, Choo, Yeun-Mun, Benjamin, Menny M., Xiong, Juan, Hamann, Mark T., Luo, Cheng, Hu, Jin-Feng
Format: Article
Published: Elsevier 2024
Subjects:
QD Chemistry
R Medicine (General)
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
Online Access:http://eprints.um.edu.my/45804/
https://doi.org/10.1016/j.bioorg.2024.107103
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Institution: Universiti Malaya

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http://eprints.um.edu.my/45804/
https://doi.org/10.1016/j.bioorg.2024.107103

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