ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes

ATG16L1 rs2241880/T300A increases susceptibility to perianal Crohn's disease: An updated meta-analysis on inflammatory bowel disease risk and clinical outcomes

BackgroundATG16L1 plays a fundamental role in the degradative intracellular pathway known as autophagy, being a mediator of inflammation and microbial homeostasis. The variant rs2241880 can diminish these capabilities, potentially contributing to inflammatory bowel disease (IBD) pathogenesis.Objecti...

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Bibliographic Details
Main Authors: Simovic, Isidora, Hilmi, Ida, Ng, Ruey Terng, Chew, Kee Seang, Wong, Shin Yee, Lee, Way Seah, Riordan, Stephen, Castano-Rodriguez, Natalia
Format: Article
Published: John Wiley & Sons Ltd 2024
Subjects:
R Medicine (General)
RJ Pediatrics
Online Access:http://eprints.um.edu.my/46002/
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Institution: Universiti Malaya

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http://eprints.um.edu.my/46002/

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