Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis

Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis

Calcitriol (1,25-dihydroxycholecalciferol) has antiproliferative and/or proapoptotic effects on many cell types and the glucocorticoid dexamethasone enhances these effects. We have shown that calcitriol modulates several key signaling proteins involved in differentiation, proliferation and apoptosis...

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Bibliographic Details
Main Authors: Flynn, G., Chung, I., Yu, W.D., Romano, M., Modzelewski, R.A., Johnson, C.S., Trump, D.L.
Format: Article
Language:English
Published: 2006
Subjects:
R Medicine
Online Access:http://eprints.um.edu.my/5070/1/Flynn-2006-Calcitriol_%281%2C25-dih.pdf
http://eprints.um.edu.my/5070/
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Institution: Universiti Malaya
Language: English

Internet

http://eprints.um.edu.my/5070/1/Flynn-2006-Calcitriol_%281%2C25-dih.pdf
http://eprints.um.edu.my/5070/

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