Application of three-dimensional culture conditions to human embryonic stem cell-derived definitive endoderm cells enhances hepatocyte differentiation and functionality

Human embryonic stemcells (hESCs) and induced pluripotent stemcells (iPSCs) provide an unlimited source for the generation of human hepatocytes, owing to their indefinite self-renewal and pluripotent properties. Both hESC-/iPSC-derived hepatocytes hold great promise in treating liver diseases as pot...

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Bibliographic Details
Main Authors: Ramasamy, T.S., Yu, J.S.L., Selden, C., Hodgson, H., Cui, W.
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:http://eprints.um.edu.my/9241/1/TS_ramasamy_tissue_engineering_2013.pdf
http://eprints.um.edu.my/9241/
http://online.liebertpub.com/doi/abs/10.1089/ten.tea.2012.0190
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Institution: Universiti Malaya
Language: English