Biosurfactants from marine Cyanobacteria collected in Malaysia, Sabah
ABSTRACT Chemical investigation of the organic extract from Moorea bouillonii, collected in Sabah, Malaysia, led to the isolation of three new chlorinated fatty acid amides, columbamides F (1), G (2), and H (3). The planar structures of 1–3 were established by a combination of mass spectrometric an...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://eprints.ums.edu.my/id/eprint/25471/1/Biosurfactants%20from%20marine%20Cyanobacteria%20collected%20in%20Malaysia%2C%20Sabah.pdf https://eprints.ums.edu.my/id/eprint/25471/2/Biosurfactants%20from%20marine%20Cyanobacteria%20collected%20in%20Malaysia%2C%20Sabah%201.pdf https://eprints.ums.edu.my/id/eprint/25471/ https://doi.org/10.1021/acs.jnatprod.0c00164 |
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| Institution: | Universiti Malaysia Sabah |
| Language: | English English |
| Summary: | ABSTRACT
Chemical investigation of the organic extract from Moorea bouillonii, collected in Sabah, Malaysia, led to the isolation of three new chlorinated fatty acid amides, columbamides F (1), G (2), and H (3). The planar structures of 1–3 were established by a combination of mass spectrometric and NMR spectroscopic analyses. The absolute configuration of 1 was determined by Marfey’s analysis of its hydrolysate and chiral-phase HPLC analysis after conversion and esterification with Ohrui’s acid, (1S,2S)-2- (anthracene-2,3-dicarboximido) cyclohexanecarboxylic acid. Compound 1 showed biosurfactant activity by an oil displacement assay. Related known fatty acid amides columbamide D and serinolamide C exhibited biosurfactant activity with critical micelle concentrations of about 0.34 and 0.78 mM, respectively. |
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