Biosurfactants from marine Cyanobacteria collected in Malaysia, Sabah

• Main Authors: Jakia Jerin Mehjabin, Liang Wei, Julie G. Petitbois, Taiki Umezawa, Fuyuhiko Matsuda, Charles S. Vairappan, Masaaki Morikawa, Tatsufumi Okino
• Format: Article
• Language: English; English
• Published: 2020
• Subjects: S Agriculture (General); SB Plant culture
• Online Access: https://eprints.ums.edu.my/id/eprint/25471/1/Biosurfactants%20from%20marine%20Cyanobacteria%20collected%20in%20Malaysia%2C%20Sabah.pdf; https://eprints.ums.edu.my/id/eprint/25471/2/Biosurfactants%20from%20marine%20Cyanobacteria%20collected%20in%20Malaysia%2C%20Sabah%201.pdf; https://eprints.ums.edu.my/id/eprint/25471/; https://doi.org/10.1021/acs.jnatprod.0c00164
• Institution: Universiti Malaysia Sabah

ABSTRACT Chemical investigation of the organic extract from Moorea bouillonii, collected in Sabah, Malaysia, led to the isolation of three new chlorinated fatty acid amides, columbamides F (1), G (2), and H (3). The planar structures of 1–3 were established by a combination of mass spectrometric and NMR spectroscopic analyses. The absolute configuration of 1 was determined by Marfey’s analysis of its hydrolysate and chiral-phase HPLC analysis after conversion and esterification with Ohrui’s acid, (1S,2S)-2- (anthracene-2,3-dicarboximido) cyclohexanecarboxylic acid. Compound 1 showed biosurfactant activity by an oil displacement assay. Related known fatty acid amides columbamide D and serinolamide C exhibited biosurfactant activity with critical micelle concentrations of about 0.34 and 0.78 mM, respectively.