Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.

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Bibliographic Details
Main Authors: Dandamudi Srilaxmi, Alugubelli Gopi Reddy, Reddymasu Sireesha, Pasupuleti Visweswara Rao, M. Ravi Kiran, Deepti Kolli, Mandava Venkata Basaveswara Rao
Format: Article
Language:English
English
Published: Pleiades Publishing 2022
Subjects:
Online Access:https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf
https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf
https://eprints.ums.edu.my/id/eprint/34182/
https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf
https://doi.org/10.1134/S107036322205019X
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Institution: Universiti Malaysia Sabah
Language: English
English
Description
Summary:A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.