Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.

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Main Authors:	Dandamudi Srilaxmi, Alugubelli Gopi Reddy, Reddymasu Sireesha, Pasupuleti Visweswara Rao, M. Ravi Kiran, Deepti Kolli, Mandava Venkata Basaveswara Rao
Format:	Article
Language:	English English
Published:	Pleiades Publishing 2022
Subjects:	RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RS400-431 Pharmaceutical chemistry
Online Access:	https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34182/ https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf https://doi.org/10.1134/S107036322205019X
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Institution:	Universiti Malaysia Sabah
Language:	English English

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spelling	my.ums.eprints.341822022-09-29T03:14:23Z https://eprints.ums.edu.my/id/eprint/34182/ Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents Dandamudi Srilaxmi Alugubelli Gopi Reddy Reddymasu Sireesha Pasupuleti Visweswara Rao M. Ravi Kiran Deepti Kolli Mandava Venkata Basaveswara Rao RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RS400-431 Pharmaceutical chemistry A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide. Pleiades Publishing 2022 Article PeerReviewed text en https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf text en https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf Dandamudi Srilaxmi and Alugubelli Gopi Reddy and Reddymasu Sireesha and Pasupuleti Visweswara Rao and M. Ravi Kiran and Deepti Kolli and Mandava Venkata Basaveswara Rao (2022) Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents. Russian Journal of General Chemistry, 92. pp. 891-897. ISSN 1070-3632 (P-ISSN) , 1608-3350 (E-ISSN) https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf https://doi.org/10.1134/S107036322205019X
institution	Universiti Malaysia Sabah
building	UMS Library
collection	Institutional Repository
continent	Asia
country	Malaysia
content_provider	Universiti Malaysia Sabah
content_source	UMS Institutional Repository
url_provider	http://eprints.ums.edu.my/
language	English English
topic	RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RS400-431 Pharmaceutical chemistry
spellingShingle	RC254-282 Neoplasms. Tumors. Oncology Including cancer and carcinogens RS400-431 Pharmaceutical chemistry Dandamudi Srilaxmi Alugubelli Gopi Reddy Reddymasu Sireesha Pasupuleti Visweswara Rao M. Ravi Kiran Deepti Kolli Mandava Venkata Basaveswara Rao Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
description	A new series of 1,3,4-oxadiazole incorporated imidazo[1,5-a]pyridine derivatives was prepared. Anticancer activity of all the obtained compounds was investigated by employing MTT assay. Among them, six compounds showed most prominent anticancer activity than etoposide.
format	Article
author	Dandamudi Srilaxmi Alugubelli Gopi Reddy Reddymasu Sireesha Pasupuleti Visweswara Rao M. Ravi Kiran Deepti Kolli Mandava Venkata Basaveswara Rao
author_facet	Dandamudi Srilaxmi Alugubelli Gopi Reddy Reddymasu Sireesha Pasupuleti Visweswara Rao M. Ravi Kiran Deepti Kolli Mandava Venkata Basaveswara Rao
author_sort	Dandamudi Srilaxmi
title	Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_short	Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_full	Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_fullStr	Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_full_unstemmed	Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents
title_sort	design and synthesis of different aryl substituted 1,3,4-oxadiazole-imidazo[1,5-a]pyridine derivatives as anticancer agents
publisher	Pleiades Publishing
publishDate	2022
url	https://eprints.ums.edu.my/id/eprint/34182/1/FULL%20TEXT.pdf https://eprints.ums.edu.my/id/eprint/34182/2/ABSTRACT.pdf https://eprints.ums.edu.my/id/eprint/34182/ https://www.pleiades.online/abstract/genchem/22/genchem0891_abstract.pdf https://doi.org/10.1134/S107036322205019X
_version_	1760231261049192448

Design and Synthesis of Different Aryl Substituted 1,3,4-Oxadiazole-imidazo[1,5-a]pyridine Derivatives as Anticancer Agents

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