Etoposide-induced apoptosis results in chromosome breaks within the AF9 gene: Its implication in chromosome rearrangement in leukaemia
Treatment with etoposide (VP-16) has been associated with translocation of the mixed lineage leukaemia (MLL) gene seen in treatment-related acute myeloid leukaemia (t-AML). Among the different partner genes, AF9 is the most common partner gene of MLL. AF9 shares similar structural element with the M...
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| Main Authors: | , |
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| Format: | E-Article |
| Published: |
Scientific Research Publishing
2012
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/8232/ http://www.scirp.org/journal/PaperInformation.aspx?PaperID=23653#.VZX17RvzqM8 |
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| Institution: | Universiti Malaysia Sarawak |