Etoposide-induced apoptosis results in chromosome breaks within the AF9 gene: Its implication in chromosome rearrangement in leukaemia
Treatment with etoposide (VP-16) has been associated with translocation of the mixed lineage leukaemia (MLL) gene seen in treatment-related acute myeloid leukaemia (t-AML). Among the different partner genes, AF9 is the most common partner gene of MLL. AF9 shares similar structural element with the M...
Saved in:
Main Authors: | , |
---|---|
Format: | E-Article |
Published: |
Scientific Research Publishing
2012
|
Subjects: | |
Online Access: | http://ir.unimas.my/id/eprint/8232/ http://www.scirp.org/journal/PaperInformation.aspx?PaperID=23653#.VZX17RvzqM8 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Universiti Malaysia Sarawak |
Be the first to leave a comment!