Effect of Pseuduvaria macrophylla in attenuating hyperglycemia mediated oxidative stress and inflammatory response in STZ-nicotinamide induced diabetic rats by upregulating insulin secretion and glucose transporter-1, 2 and 4 proteins expression
antidiabetic agent; C peptide; glibenclamide; glucose; glucose transporter 1; glucose transporter 2; glucose transporter 4; glutathione; insulin; interleukin 1beta; interleukin 6; nicotinamide; plant extract; Pseuduvaria macrophylla extract; transforming growth factor beta1; tumor necrosis factor; u...
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| Main Authors: | , , , , , |
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| Format: | Article |
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University of South Bohemia
2023
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| Institution: | Universiti Tenaga Nasional |
| Summary: | antidiabetic agent; C peptide; glibenclamide; glucose; glucose transporter 1; glucose transporter 2; glucose transporter 4; glutathione; insulin; interleukin 1beta; interleukin 6; nicotinamide; plant extract; Pseuduvaria macrophylla extract; transforming growth factor beta1; tumor necrosis factor; unclassified drug; animal cell; animal experiment; animal model; animal tissue; Annonaceae; antidiabetic activity; Article; body weight; controlled study; glucose blood level; histopathology; immunohistochemistry; inflammation; insulin blood level; insulin level; insulin release; insulin signaling; lipid peroxidation; non insulin dependent diabetes mellitus; nonhuman; oxidative stress; pancreas islet; pancreas islet beta cell; pancreas tissue; peroxidation; protein expression; Pseuduvaria macrophylla; rat; toxicity testing |
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