HIF-1 sensor in detecting hypoxia tolerance at high altitude

• Main Authors: Shaharuddin, Shazreen, Nik Abd Rahman, Nik Mohd Afizan, Masarudin, Mas Jaffri, Alamassi, Mohammedarfat N., Ahmad Saad, Fathinul Fikri
• Format: Article
• Published: Aerospace Medical Association 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/108173/; https://www.ingentaconnect.com/content/asma/amhp/2023/00000094/00000006/art00014;jsessionid=71ydx8oeue8j.x-ic-live-03
• Institution: Universiti Putra Malaysia

INTRODUCTION: An episode of prolonged exposure to high altitude can cause hypoxia and have significant health consequences. In people with a high-altitude disorder, the body reacts by producing a protein called hypoxia-inducible factor (HIF), which triggers a series of physiological changes and serv...