Synthesis and biological evaluation of curcumin-like diarylpentanoid analogues for anti-inflammatory, antioxidant and anti-tyrosinase activities

A series of 46 curcumin related diarylpentanoidanalogues were synthesized and evaluated for their anti-inflammatory, antioxidant and anti-tyrosinaseactivities. Among these compounds 2, 13 and 33 exhibited potent NO inhibitory effect on IFN-γ/LPS-activated RAW 264.7 cells as compared to l-NAME and cu...

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Bibliographic Details
Main Authors: Ka-Heng, Lee, Ab. Aziz, Farida Haryani, Ahmad, Syahida, Abas, Faridah, Shaari, Khozirah, Israf Ali, Daud Ahmad, Lajis, Nordin
Format: Article
Language:English
English
Published: Elsevier 2009
Online Access:http://psasir.upm.edu.my/id/eprint/16920/1/Synthesis%20and%20biological%20evaluation%20of%20curcumin.pdf
http://psasir.upm.edu.my/id/eprint/16920/
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Institution: Universiti Putra Malaysia
Language: English
English