Effect of Bcl-2 overexpression on cell cycle and antibody productivity in chemostat cultures of myeloma NS0 cells

Chemostat cultures of NS0 cell lines were carried out at dilution rates ranging from 0.8 d-1 to 0.2 d-1. Compared with the control, the viable cell density of the Bcl-2 cell line was approximately 10% higher at 0.8 d-1 and increased to 55% when the dilution rate was reduced to 0.2 d-1. As the diluti...

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Bibliographic Details
Main Authors: Tey, Beng Ti, Al-Rubeai, Mohamed
Format: Article
Language:English
English
Published: The Society for Biotechnology 2005
Online Access:http://psasir.upm.edu.my/id/eprint/18322/1/Effect%20of%20Bcl.pdf
http://psasir.upm.edu.my/id/eprint/18322/
http://dx.doi.org/10.1263/jbb.100.303
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Institution: Universiti Putra Malaysia
Language: English
English