Dentatin isolated from Clausena excavata induces apoptosis in MCF-7 cellsthrough the intrinsic pathway with involvement of NF-kB signalling andG0/G1 cell cycle arrest : a bioassay-guided approach
Ethnopharmacological relevance: Clausena excavata Burm. f. has been used in folk medicines in eastern Thailand for the treatment of cancer. Materials and methods: To investigate the apoptosis mechanism, we isolated dentatin (DTN) from this plant using a bioassay-guided approach. DTN-induced cytot...
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Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013
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Online Access: | http://psasir.upm.edu.my/id/eprint/30034/1/Dentatin%20isolated%20from%20Clausena%20excavata%20induces%20apoptosis%20in%20MCF.pdf http://psasir.upm.edu.my/id/eprint/30034/ http://dx.doi.org/10.1016/j.jep.2012.11.020 |
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Institution: | Universiti Putra Malaysia |
Language: | English |
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