NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide

NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide

Andrographolide (AGP) is the main bioactive constituent isolated from the traditional medicinal, Andrographis paniculata which contributes towards its various biological activities, including anticancer property. In this study, a series of new AGP derivatives were semi-synthesised and screened again...

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Bibliographic Details
Main Authors: Wong, Charng Choon, Sagineedu, Sreenivasa Rao, Sumon, Shariful Hasan, Mohamad Sidik, Shiran, Phillips, Roger, Lajis, Nordin, Stanslas, Johnson
Format: Article
Published: Elsevier 2014
Online Access:http://psasir.upm.edu.my/id/eprint/34632/
http://www.sciencedirect.com/science/article/pii/S1382668914001707
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Institution: Universiti Putra Malaysia

Internet

http://psasir.upm.edu.my/id/eprint/34632/
http://www.sciencedirect.com/science/article/pii/S1382668914001707

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