Antioxidant and anti-ulcer effects of ethyl acetate fraction of Merremia tridentata (L.) Hallier f. root
The present study was aimed to determine the antioxidant and anti-ulcer effects of Merremia tridentata root (Arrow-leaf Morning Glory). Antioxidant potential of crude acetone extract and its fractions was evaluated by using various in vitro assays. In the anti-ulcer study, pre-treatment with ethyl a...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/36491/1/Antioxidant%20and%20Anti-Ulcer%20Effects%20of%20Ethyl%20Acetate%20Fraction%20of.pdf http://psasir.upm.edu.my/id/eprint/36491/ |
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| Institution: | Universiti Putra Malaysia |
| Language: | English |
| Summary: | The present study was aimed to determine the antioxidant and anti-ulcer effects of Merremia tridentata root (Arrow-leaf Morning Glory). Antioxidant potential of crude acetone extract and its fractions was evaluated by using various in vitro assays. In the anti-ulcer study, pre-treatment with ethyl acetate fraction (MEF) (50, 100 and 200 mg/kg b.wt.) significantly protected the ethanol-induced gastric ulcer in rats. Simultaneously, the antioxidant enzyme levels of superoxide dismutase, catalase and glutathione in the stomach tissues were significantly increased while pre-treated with MEF. From the results, MEF has the therapeutical potential to prevent gastric ulceration induced by ethanol. |
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