Application of Plackett Burman design for antioxidant extraction from Actinodaphne sesquipedalis leaves

Actinodaphne sesquipedalis Hook. F. Var. Glabra (Kochummen), also known as “Medang payung” by the Malay people, belongs to the Lauraceae family. In this study, a Plackett-Burman design was used to evaluate the significant extraction parameters in achieving maximum DPPH radical scavenging activity fr...

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Bibliographic Details
Main Authors: Jamaludin, Siti Fatihah Balqis, Abd Gani, Siti Salwa, Zaidan, Uswatun Hasanah, Bawon, Paiman
Format: Article
Language:English
Published: Blue Eyes Intelligence Engineering & Sciences Publication 2019
Online Access:http://psasir.upm.edu.my/id/eprint/80706/1/PLACKETT.pdf
http://psasir.upm.edu.my/id/eprint/80706/
https://www.ijeat.org/wp-content/uploads/papers/v8i6S3/F10080986S319.pdf
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Institution: Universiti Putra Malaysia
Language: English
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Summary:Actinodaphne sesquipedalis Hook. F. Var. Glabra (Kochummen), also known as “Medang payung” by the Malay people, belongs to the Lauraceae family. In this study, a Plackett-Burman design was used to evaluate the significant extraction parameters in achieving maximum DPPH radical scavenging activity from ethanol leaves extract of A. sesquipedalis. Microwave-assisted extraction technique was employed using aqueous ethanol. The independent parameters were microwave power level (30–60 W), feed-to-solvent ratio (1:30 g/ml), irradiation time (30-90 s) and ethanol concentration (20–80%). Amongst the examined parameters, ethanol concentration, microwave power level, and irradiation/extraction time were significant, whereas, feed-to-solvent ratio was insignificant. Therefore, antioxidants from the ethanolic extraction leaves of A. sesquipedalis using microwave technique are significantly affected by ethanol concentration, irradiation time and microwave power.