Analysis of urinary metabolic alteration in type 2 diabetic rats treated with metformin using the metabolomics of quantitative spectral deconvolution 1H NMR spectroscopy

Analysis of urinary metabolic alteration in type 2 diabetic rats treated with metformin using the metabolomics of quantitative spectral deconvolution 1H NMR spectroscopy

Metformin has been used clinically as the first-choice drug to treat type 2 diabetes patients. It is not metabolized in liver and the residue which is excreted unchanged in the urine. Identification and quantification of metformin in the urine can be used as a unique marker for the metformin treated...

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Main Authors: M., Maulidiani, Abas, Faridah, R., Rudiyanto, Abd Kadir, Nurul Huda, Zolkeflee, Nur Khaleeda Zulaikha, Lajis, Nordin
Format: Article
Language:English
Published: Elsevier 2020
Online Access:http://psasir.upm.edu.my/id/eprint/87869/1/ABSTRACT.pdf
http://psasir.upm.edu.my/id/eprint/87869/
https://www.sciencedirect.com/science/article/pii/S0026265X19316480
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Institution: Universiti Putra Malaysia
Language: English

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http://psasir.upm.edu.my/id/eprint/87869/1/ABSTRACT.pdf
http://psasir.upm.edu.my/id/eprint/87869/
https://www.sciencedirect.com/science/article/pii/S0026265X19316480

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