Development of Polymeric Nanoparticles of Garcinia mangostana Xanthones in Eudragit RL100/RS100 for Anti-Colon Cancer Drug Delivery

Development of Polymeric Nanoparticles of Garcinia mangostana Xanthones in Eudragit RL100/RS100 for Anti-Colon Cancer Drug Delivery

Xanthones are a group of oxygenated heterocyclic compounds with anticancer properties, but poor aqueous solubility and low oral bioavailability hinder their therapeutic application. This study sought to prepare a xanthones extract (81%

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Bibliographic Details
Main Authors:	Abdalrahim F. A., Aisha, Abdulmajid, Amin Malik Shah, Ismail, Zhari, Alrokayan, Salman A., Abu-Salah, Khalid M.
Format:	Article
Language:	English
Published:	Hindawi Publishing Corporation 2015
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/38679/1/Development_of_Polymeric_Nanoparticles_of_Garcinia_mangostana_Xanthones_in_Eudragit.pdf http://eprints.usm.my/38679/ http://dx.doi.org/10.1155/2015/701979
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Institution:	Universiti Sains Malaysia
Language:	English

Description
Summary:	Xanthones are a group of oxygenated heterocyclic compounds with anticancer properties, but poor aqueous solubility and low oral bioavailability hinder their therapeutic application. This study sought to prepare a xanthones extract (81%