Metabolites production improvement by identifying minimal genomes and essential genes using flux balance analysis

• Main Authors: Salleh, A. H. M., Mohamad, M. S., Deris, S., Illias, R. M.
• Format: Article
• Published: Inderscience Publishers 2015
• Subjects: QA75 Electronic computers. Computer science
• Online Access: http://eprints.utm.my/id/eprint/58537/; http://dx.doi.org/10.1504/IJDMB.2015.068955
• Institution: Universiti Teknologi Malaysia

With the advancement in metabolic engineering technologies, reconstruction of the genome of host organisms to achieve desired phenotypes can be made. However, due to the complexity and size of the genome scale metabolic network, significant components tend to be invisible. We proposed an approach to...